Number One: Floyd Mayweather Jr. vs. Juan Manuel Marquez
The undefeated Floyd Mayweather Jr. returns to the ring after nearly two years of retirement to take on Lightweight Champion Juan Manuel Marquez at a catchweight of 144 pounds. Coming in heavy, Mayweather opts to pay Marquez the penalty rather than try and make weight. The size difference - in addition to the enormous speed discrepancy - proves too much for Marquez to overcome as he is floored by Mayweather in the second round and beaten to the punch all night long. After twelve rounds, Mayweather has pitched a shutout and takes a unanimous decision over the man that has plagued Manny Pacquiao through two fights.